Glycerol monostearate, also known as GMS or glycine, is a compound commonly used in the food and pharmaceutical industries as an emulsifier, thickening agent, and stabilizer. Chemically, it is a glycerol molecule esterified with stearic acid, a type of fatty acid. It is typically produced from natural sources such as vegetable oils or animal fats.

Glycerol monostearate is commonly used in sports nutrition and bodybuilding supplements for a few reasons:

1. Muscle cell hydration: Glycerol monostearate may promote cell volumization, particularly in muscle cells. By drawing water into the muscle cells, it can create a temporary “pumped” or full appearance, which some athletes and bodybuilders find desirable for aesthetic purposes. This effect can also contribute to the sensation of muscle fullness during workouts.*
2. Improved exercise performance: The hydration and cell volumization effects of glycerol monostearate may translate to improved exercise performance. Enhanced hydration can help maintain electrolyte balance and prevent performance decrements associated with dehydration.*

Taking glycerol monostearate may have some potential downsides for individuals including:

1. Gastrointestinal issues: Some individuals may experience gastrointestinal discomfort, such as bloating, diarrhea, or stomach cramps, when taking glycerol supplements. These side effects are usually mild and can often be minimized by taking glycerol monostearate with plenty of water and/or with meals.
2. Dehydration and electrolyte imbalance: Excessive consumption of glycerol monostearate without adequate fluid intake may lead to dehydration. It’s important to drink enough water when using glycerol supplements to maintain proper hydration balance.
3. Individual variability: Not everyone responds to glycerol supplementation in the same way. While many individuals experience benefits, some may not see significant improvements.